Fe/Cu nanocomposites prepared from sweet potato leaves were investigated for the removal of Rhodamine B(RhB) from aqueous solution. The effects of various parameters such as adsorption time , adsorbent dosage and pHwere optimized by response surface methodology (RSM). The adsorption equilibrium data were well fitted with Sipsmodel, and the thermodynamic study indicated that the adsorption process was a spontaneous endothermic process.The pseudo-second order kinetics model could describe well the adsorption process of RhB onto Fe/ Cu nanocompos-ites. At 298 K, the maximum adsorption capacity of Fe/ Cu nanocomposites for RhB was 484.18 mg/g, indicatingthat Fe/Cu nanocomposites had a good application in RhB waste water treatment.