骨替代生物陶瓷材料的研究现状-《郑州大学学报(工学版)》

文章信息/Info

作者:: 高金星¹; 李丽亚¹; 穆菁华¹; 徐恩霞¹; 刘新红¹; 马成良¹; 张灿²; 张丽果²; 1.郑州大学材料科学与工程学院,河南郑州 450052, 2.郑州大学河南省医药科学研究院,河南郑州 450001

Author(s):: GAO Jinxing¹; LI Liya¹; MU Jinghua¹; XU Enxia¹; LIU Xinhong¹; MA Chengliang¹; ZHANG Can²; ZHANG Liguo²; 1.School of Materials Science and Engineering, Zhengzhou University, Zhengzhou 450052, Henan, 2.Institute of Medical Sciences, Henan Provincial Medical Sciences, Zhengzhou University, 450001, Zhengzhou, Henan

Keywords:: bone substitute materials; bioceramic materials; compound material; biological properties; physical and chemical properties

摘要:: 针对骨替代生物材料的发展需求,简述了骨替代用高分子材料、金属材料、生物陶瓷材料和复合材料的发展现状,着重介绍了生物陶瓷材料作为骨替代材料在力学性能、化学性能和生物性能方面的优势。生物陶瓷材料因密度和成分与人骨相近、生物相容性显著、机械强度高、化学性质稳定等特点,在当今的骨替代材料领域中扮演着重要角色。对以磷酸盐、硅酸盐、氧化物和非氧化物为代表的生物陶瓷材料的研究现状进行了系统地探讨,并对生物陶瓷材料及其复合材料用于骨替代生物材料的优势和局限性进行讨论,最后对生物陶瓷材料未来的发展方向进行了展望。

Abstract:: In view of the development demand of biomaterials for bone substitute, the development status of polymer materials, metal materials, bioceramic materials and composite materials for bone replacement were summarized, and the advantages of bioceramic materials in mechanical properties, chemical properties and biological properties as bone substitute materials were emphatically introduced. The bioceramic materials play an important role in the field of bone substitute materials due to their similar density and composition to human bone, significant biocompatibility, high mechanical strength, and stable chemical properties. In this paper, the research status of bioceramic materials represented by phosphate, silicate, oxides and non-oxides is systematically discussed, and the advantages and limitations of bioceramic materials and their composites as bone substitute biomaterials are discussed. Finally, the future development direction of bioceramic materials is prospected.